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doctorgirl78
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Q 83 radio mets
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11.15.03 (5 years ago)
#1
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most sensitive test for mets deposit
isotope
ct scan
skeletal survey
tomography
if i rember right,xray was the best........what about this q
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neodoc
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advances in radiology!
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11.16.03 (5 years ago)
#2
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hii!
this question is too important form academic point of view!
most recent information onlin suggests that and i quote
website
..........Preferred Examination: Technetium-99m bone scintiscanning (ie, radionuclide bone scanning) is widely regarded as the most cost-effective and available whole-body screening test for the assessment of bone metastases. Conventional radiography is the best modality for characterizing lesions that are depicted on bone scintiscans. Combined analysis and reporting of findings on radiographs and 99mTc bone scintiscans improve the diagnostic accuracy in detecting bone metastases and assessing the response to therapy.
CT and MRI are useful in evaluating suspicious bone scintiscan findings that appear equivocal on radiographs. MRI can also help in detecting metastatic lesions before changes bone metabolism make the lesions detectable on bone scintiscans. CT is useful in guiding needle biopsy, particularly in vertebral lesions. MRI is helpful in determining the extent of local disease in planning surgery or radiation therapy.
The first screening test used for the detection of bone metastases depends on the relative availability of MRI and 99mTc bone scintiscanning. The selection will become less of an issue when more MRI units are established and when its cost decreases. Factors such as cost, relatively long imaging times, and patient throughput considerations are important. Compared with 99mTc bone scintigraphy, MRI is estimated to cost 2-3 times as much, and FDG PET, 8 times as much.
Limitations of Techniques: Radiographs are relatively insensitive in the detection of early or small metastatic lesions. Although CT scans are superior to radiographs, CT is also relatively insensitive in showing small intramedullary lesions, and it has the disadvantage of limited skeletal coverage. Bone scintiscan findings are sensitive but nonspecific. Whole-body MRI and 2-[fluorine 18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) are accurate techniques that are currently limited by their high cost.
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doctorgirl78
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11.16.03 (5 years ago)
#3
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you stil left me wondering as to what to mark in the test........... 8)
but the info was great...thanks..
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akanksha
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type of lesion!
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11.19.03 (5 years ago)
#4
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well,
the metastatic lesion in the bones can be both osteolytic n osteoblastic. 
n for osteolytic lesions,X rays are the most sensitive. 8)
while for osteoblastic,bone scans are the most sensitive. 
read in harrisions!
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akanksha
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think!
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11.19.03 (5 years ago)
#5
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well,a food for thought....
how wud u differentiate an osteolytic bone lesion from osteoporosis in an X ray? 
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doctorgirl78
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11.20.03 (5 years ago)
#6
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osteoprorosis is diffuse rarefaction...........osteolytic lesion is a focal lesion.........  
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akanksha
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ther u!
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11.20.03 (5 years ago)
#7
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gud catch,doc! 8)
its gud when u get a 'generalised' X ray!but suppose when u tuk an X ray of sum site, in an old female,with a pathological fracture,n dat bone is diseased!how wud u know,if its due to osteoporosis or metastatic deposits?
well,harri says,in osteoporosis,cortex remains intact even in the late stage of the disease.
while in osteolytic type of bone metastasis,cortex gets eroded very early!
happy studying! 
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doctorgirl78
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12.05.03 (5 years ago)
#8
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when Santa comes around on Xmas..........u wanna say i have been a good person.haina............
so read the link and answer the question.........
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decembermist
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10.27.04 (4 years ago)
#9
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so wat shud v mark..xray or scan
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decembermist
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11.01.04 (4 years ago)
#10
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????
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