Page 1 of 2: O & G AIIMs.

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

HRT is helpfull in all of the following except :

A. Vaginal atrophy.
B. Flushing
C. Osteoporosis
D Coronary heart disease

ankursabherwal · Credits: 8514 My Scrapbook

answer should be d as rest are all indications of HRT.

gynguru · Credits: 1348 My Scrapbook

i donot agree with this answer. novaks clearly states that HRT reduces the risk of MI & stroke by 50% in those on HRT when compared to those not on HRT. in fact all the conditions listed are valid indications for HRT. i feel it is best to leave such Q where there is no single right answer. what say?
those who have a high risk of MI are to be considered for HRT

Staphylococcus · Credits: 5796 My Scrapbook My Reading List 1 Books

hmm .. we always have to choose a relatively right answer...
in this 1st 3 are clear cut indications.. so i wud still go for CAD

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

Any particular reference of HRT...

Its an imporant topic in AIIMS

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

For postmenopausal women who have had a heart attack or stroke, American heart association guidelines recommend that HRT not be initiated for secondary prevention.
This recommendation is based, in part, on the results of the Heart and Estrogen Replacement Study (HERS), a large-scale study that found no benefit of HRT among women with heart disease. For preventing a first heart attack or stroke, the association

zhabrawi · Credits: 2978 My Scrapbook

I agree with cingulate that the answer should be CAD,as although HRT does alter the lipid profile with a higher level of high density lipoproteins and lower cholesterol,there is no definetive evidence that HRT reduces the risk of IHD in low risk women.
(Ref.Lecture notes in Og&Gyn)

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

The Heart and Estrogen/Progestin Replacement Study (HERS)

The Heart and Estrogen/Progestin Replacement Study (HERS-I), reported in the Journal of the American Medical Association (JAMA), looked at 2,763 postmenopausal women with pre-existing coronary artery disease who were randomly assigned to take either estrogen/progestin HRT or a placebo (secondary prevention trial).

Researchers found that the women receiving HRT actually had a higher risk of heart attacks and cardiac events during the first year of the study, compared to women taking the placebo. During the next four to five years of the study, however, the risk for women in the HRT group diminished. At the end of 4.1 years, researchers found no overall reduction in the rate of coronary heart disease events among the women receiving HRT compared to those receiving the placebo, despite that fact that HRT reduced LDL (“bad”) cholesterol while increasing levels of HDL (“good”) cholesterol.

In 2002, a followup study was published in JAMA. The Heart and Estrogen/Progestin Replacement Study (HERS-II) examined an additional 2.7 years. In contrast to the first findings, the researchers discovered that the HRT group failed to reduce the risk of cardiovascular events as compared to the placebo group. Therefore, HRT should not be prescribed in postmenopausal women to reduce cardiovascular risk.

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

HERS

cingulate_gyrus2006 · Credits: 22810 My Scrapbook

All about HRT here...

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