Page 1 of 35: E NOTES--- AIPGME 2008

aminhars · Credits: 13255 My Scrapbook

hey friends i m starting a new thread .post some good e-notes u have too.this may help us getting good marks in aipgme.....if u like this reply - i will continue it. n u can also join it....

• Abciximab ReoPro 1994 chimeric inhibition of glycoprotein IIb/IIIa Cardiovascular disease

• Infliximab Remicade 1998 chimeric I inhibition of TNF-a Inflammatory diseases Adalimumab Humira 2002 human inhibition of TNF-a signalling Inflammatory diseases

• Natalizumab Tysabri 2006 humanized T cell VLA4 receptor Inflammatory diseases . (esp autoimmune-related multiple sclerosis therapy)

• Omalizumab Xolair 2004 humanized Ig E Inflammatory diseases . (mainly allergy-related asthma therapy)

• Eculizumab Soliris 2007 humanized complement C5 Inflammatory diseases . (PNH)

• Efalizumab Raptiva 2002 humanized CD11a Inflammatory diseases . (psoriasis)

• Alemtuzumab Campath 2001 humanized CD52 CLL Gemtuzumab Mylotarg 2000 humanized CD33 AML . (with calicheamicin)

• Ri - tuximab Rituxan, Mabthera 1997 chimeric CD20 NHL Ibritumomab tiuxetan Zevalin 2002murine CD20 NHL (with yttrium-90 or indium-111) Tostumomab Bexxar 2003 murine CD20 NHL

• Daclizumab Zenapax 1997 humanized IL-2 receptor Transplant rejection Basiliximab Simulect 1998 chimeric IL-2 receptor Transplant rejection MuromonabOrthoclone OKT3 1986 murine CD3 Receptor Transplant rejection

• Bevaciz umab Avastin 2004 humanized vascular endothelial growth factor Colorectal cancer Panitumumab Vectibix 2006human epidermal growth factor receptor Colorectal cancer Cetuximab Erbitux 2004 chimeric epidermal growth factor receptor Colorectal cancer

• Ranibizumab Lucentis 2006 humanized vascular endothelial growth factor Macular degeneration

• Palivizumab Synagis 1998 humanized epitope of F protein of RSV Viral infection (espRSV)

• Trastuzumab Herceptin 1998 humanized ErbB2 Breast cancer

anything with mab suffix is mono. antibody

look for immediate before mab

--if "u" ---human derived
--if"mo"---murine
---if "i" ---chimeric

aminhars · Credits: 13255 My Scrapbook

Pseudocyesis Abdominal distension Mimicking Pregnancy
Pseudo papillitis Hypermetropia
Pseudo hypopyon Tuberculous corneal ulcer
Pseudo bubo Granuloma inguinale
Pseudo fractures Osteomalacia (Looser's Zones)
PseudoMembranous conjunctivitis Pneumococcal
Pseudotuberculids Bilharziasis of bladder
Pseudocoxalgia Perthe’s disease
Pseudoparalysis Scurvy, Osteomyelitis, Congenital Syphilis, Acute Rheumatic fever and Trichinosis
Pseudohemophilia Von Willebrand’s disease
Pseudoachromasia is seen in a)Tinea versicolor
b) Pityriasis
c) seborrhic dermatitis
Pseudohemoptysis is due to pigmentation caused by Serratia
Pseudomyopia is due to excess accommodation

aminhars · Credits: 13255 My Scrapbook

Inclusion Bodies

Viral Inclusion Bodies

A)Intra Cytoplasmic

Rabies ---Negri bodies
Small pox ---Gaurnier bodies
Molluscum Contagiosum---------- Henderson Roterson bodies
Fowl pox-- --Bollinger bodies
Trachoma--Halberstaedter- Prowazek Bodies

B)Intra Nuclear Inclusions

Cowdry type A
Herpes Virus( Lipschutz Inclusions)
Yellow fever ( Torres Bodies)

Cowdrey Type B
Adeno Virus ( Basophilic)
Poliovirus ( acidophilic)

C)Both Intra Nuclear and Cytoplasmic

Measles Virus
________________________________________
Parasites

Morula cells with Ig M Deposits--- Tryponosomiasis

Leishman Donovan Bodies-------- Kala –azar(amastigote in macrophage)

Psittacosis------------- LCL bodies ( Levinthal Cole Lille Bodies) .

________________________________________

Owl-eye inclusions---
a)CMV
b) Herpes

aminhars · Credits: 13255 My Scrapbook

• Total population - 1049 million (2002)

• Crude birth rate - 25 (2002)
• Crude death rate - 8.1 (2002)

• Total fertility rate - 3.1 (2002)
• CPR - 46.2 % (2002) (52 is also given but mohfw says 46.2)

• IMR - 63 (2003)
• Neonatal mortality - 45 (1999)
• Child mortality rate - 19.5 (2000)
• U-5 mortality - 93 (2002)
• MMR - 407 (1998)
• Infants fully immunized – 56 % (2002)
National Vector Borne Diseases Control Program from 2003-04 by Inclusion of JE and dengue with other three ongoing programs (Malaria, Filaria, Kalaazar)

*Prevalence of Leprosy - 2.3/10,000 (march 2004)

*API- 1.62 (2003). Target in 10th plan is API <1.3

*Eye donation fortnight - 25th Aug to 8th Sept
*According to national survey on blindness (2001-02) estimated prevalence of blindness = 1.1%

* DOTS treatment success rate = 86 % (2002)

aminhars · Credits: 13255 My Scrapbook

PEDIATRICS IMP landmarks
Intrauterine landmarks

(1) USG Evidence of pregnancy (sac and fetal pole)==4th or 5th wk.

(2) Heart sounds first heard==8 to 10 wk Gest.age with a Doppler ultrasound device
& 18 to 20 wk gest.age with a stethoscope.

(3) Gender can be distinguished==10 weeks.

(4) Breathing movements==15-18 weeks.

(5) Swallowing movements==15-18 weeks.

Imp age landmarks in a child

(1) Adult haemoglobin production starts/
the switch over of fetal Hb. to adult haemoglobin production starts==16-20weeks of gestation.

(2) Surfactant production starts==22 to 28 weeks gestation.

(3) Surfactant production reaches maturity levels==34 to 35 wk gestation.

(4) Foramen ovale- functional closure==At birth.

(5) Taste perception develops= at birth.

(6) Newborn looses 10% body weight==1st week.

(7) Regains by==10th day.

(8) Adult haemoglobin is equal to fetal ==2 months.

(9) Post fontanelle closes==3 mths.

(10) Switch over of fetal Hb. to adult haemoglobin production completed ==6-12 mths postnatally.

(11) Foramen ovale- anatomical closure==1 year to 23 months after birth.

(12) Ant fontanelle closes==18 months.

(13) Handedness develops==2 years.

(14) Abstract thinking ==3 years.

(15) Decision making ==3 years.

(16) All milk teeth erupted by= 2 years.

(17) Visual acuity attained to adult==7 years.

(18) For lungs maturity== L/S ratio should be > 2:1

drserious · Credits: 435 My Scrapbook

hi aminhars,
why don't you join mpge. u will get rewarded for your work there i am sure.

the site address is written on my avatar.

do have a visit

drserious · Credits: 435 My Scrapbook

and also mpge is presently focusing on aipgmee 08 only

dr_mina · Credits: 200 My Scrapbook

what will be the reward for contributing mcq?

drserious · Credits: 435 My Scrapbook

they have started MCQ finder title and MCQ solver title competition just half hour before.

you can apply now , competition will remain for one week.

also they give special powers to good members

. apply now for competition and participate.

i know you can win

ryma890 · Credits: 44075 My Scrapbook

aminhar that paeds post is gr8............

		Sign In New User? Sign Up Sign in to access your control panel and messenger!
				TechZone \| SpiderNevi \| HowTo? \| Scrapbook!