Page 1 of 1: Paeds.

docnoor · Credits: 3871 My Scrapbook

How to differentiate between constitutional and familial causes of short stature?

a. karyotype.
b. bone age.
c. hormonal assays.

smartyroy · Credits: 13861 My Scrapbook

a.........

met5 · Credits: 3051 My Scrapbook

b...

ruks83 · Credits: 2232 My Scrapbook

agreed with met5 ..bone age.

Kai1111 · Credits: 2036 My Scrapbook

b) bone age

"The hallmarks of familial short stature (also referred to as genetic short stature) include bone age appropriate for chronologic age, normal growth velocity, and predicted adult height appropriate to the familial pattern (using the Bayley-Pinneau or Tanner-Goldstein-Whitehouse tables). By contrast, constitutional growth delay is characterized by delayed bone age, normal growth velocity, and predicted adult height appropriate to the familial pattern (see Image 2). Patients with constitutional growth delay typically have a first-degree or second-degree relative with constitutional growth delay (eg, menarche reached when older than 15 y, adult height attained in male relatives when older than 18 y)."
Excellent article:

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