Page 1 of 1: gynae/obs- menopause

parnika · Credits: 2911 My Scrapbook

Menopause
a-most common at 55 years
b-increased FSH and LH
C-increased fsh and decreased LH
D-Increased levl of HDL
E-Increased incidence of IHD
F-Increase incidnce of renal disease
g-increase incidence of osteoporosis
h-increase incidnce of vaginal discharge

aceofbase · Credits: 1715 My Scrapbook

in this only E F G ARE CORRECT

parnika · Credits: 2911 My Scrapbook

thanx any refrence..well i have a doubt about lh levels after menopause...do they rise same as fsh ??

aceofbase · Credits: 1715 My Scrapbook

ILL VERIFY AND LET YOU KNOW

drjanak · Credits: 3151 My Scrapbook

Menopause
a-most common at 55 years
b-increased FSH and LH
C-increased fsh and decreased LH
D-Increased levl of HDL
E-Increased incidence of IHD
F-Increase incidnce of renal disease
g-increase incidence of osteoporosis
h-increase incidnce of vaginal discharge

Answers:
True - B, E, G
Reference:
Clinical Gynecological Endocrinology and Infertility 6th ed - Leon Speroff

"The Age of Menopause
The Massachussetts Women’s Health Study provides us with data from 2570 women. The median age for menopause in this study was 51.3 years. … Keep in mind that a median age of menopause means that only half the women have reached menopause at this age. In the classic longitudinal study by Treolar, the “average” age of menopause was 50.7, and the range that included 95% of women was 44 to 56.

Hormone production after Menopause
Eventually there is a 10-20-fold increase in FSH and approximately a 3-fold increase in LH, reaching a maximal level 1-3 years after menopause, after which there is a gradual, but slight, decline in both gonadotrophins. Elevated levels of both FSH and LH at this time in life are conclusive evidence of ovarian failure.

Cardiovascular Disease
During the reproductive years women are “protected” from coronary heart disease….. a significant contribution to this protection can be assigned to the higher HDL levels in younger women, an effect of estrogen.
…. After menopause the risk of CHD doubles for women as the atherogenic lipids about age 60 reach levels greater than those in men.

Osteoporosis
Beyond age 30, trabecular resporption begins to exceeds formation by about 0.7% per year. This adverse relationship accelerates after menopause and upto 5% of trabecular bone and 1-1.5% of total bone mass loss will occur per year after menopause. This accelerated loss will continue for 10-15 years, after which bone loss is considerably diminished but continues as the age related loss. For the first 20 years after cessation of menses, menopause related bone loss results in 50% reduction of trabecular bone and 30% reduction of cortical bone.

Atrophic changes
With extremely low estrogen in the late postmenopausal age, atrophy of vaginal mucosal surfaces takes plac, accompanied by vaginitis, prurutis, dyspareunia and stenosis."

The last paragraph implies dryness of the vagina. Hence discharge is unlikely. a pathological discharge due to vaginitis is possible, but overall I would still opt for "increased discharge" after menopause as false.

hope the above references anwer your queries.

parnika · Credits: 2911 My Scrapbook

thanx very much janak for explaining it so nicely..what about option option f-increase incidence of renal disease..??

drjanak · Credits: 3151 My Scrapbook

Sorry, I have not come across any direct corelation of menopause as causing higher incidence of renal disease. Logically I cannot think of any reason for increased incidence of renal disease after the ovarian function diminishes. Estrogen is not known to directly influence the kidneys and hence its absence should not be detrimental.
Incidentally chronic renal failure or any other renal disease could lead to or exacerbate the osteoporosis and bone loss in the menopausal age group.
Hope this helps you.

parnika · Credits: 2911 My Scrapbook

thanx very much drjanak

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