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dhaneshvijayan
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Newer Drugs.. Nagging
Names and Actions.. A Must Know For AI
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05.14.08 (5 months ago)
#1
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NEWER DRUGS
1. Lenolidomide: An IMID – Immunomodulatory derivative of Thalidomide.
2. Atomoxetine: CNS noradrenaline (NA) reuptake inhibitor, first and only FDA approved non-stimulant drug for treatment of ADHD.
3. Modafinil: for patients with narcolepsy, sleep apnea, and shift work sleep disorder.
4. Guanfacine: a selective alpha-2A-adrenoceptor agonist of CNS for ADHD.
5. Eplerenone: Aldosterone antagonist.
6. Nesiritide: Recombinant BNP.
7. Enoximone: PDE IIIa inhibitor (Amrinone/Milrinone)
8. Levosimendan: Calcium sensitizer.
9. Istaroxime: Na+/K+ -ATPase inhibitor (E.g. Digoxin), FIRST DRUG to target LUSITROPY.
10. Carperitide: Recombinant BNP.
I will COntinue to post ... Please Contribute.... Dhanesh V
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dhaneshvijayan
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05.14.08 (5 months ago)
#2
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Friends I will Try to Post a list of Monoclonal Antibodies which i prepared soon..
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vicks99
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05.14.08 (4 months ago)
#3
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NEW HIV DRUGS
MARAVIROC-ENTRY INHIBITOR
RALTEGRAVIR-INTEGRASE INHIBITOR
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dhaneshvijayan
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NEWER DRUGS CONTD...
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05.14.08 (4 months ago)
#4
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11. Tezosentan: Endothelin-1-Antagonist, Cardiac remodeling inhibitor.
12. Bosentan: Endothelin-1-Antagonist, Cardiac remodeling inhibitor. Used for Rx of PPH.
13. Perhexiline: pFOX (Fatty acid oxidase) inhibitor.
14. Etomoxir: pFOX (Fatty acid oxidase) inhibitor.
15. Ularitide: Recombinant Urodilantin, a natriuretic peptide similar to ANP, BNP.
16. Candoxatrilat: Inhibit Neutral Endopeptidase, increases ANP.
17. Omapatrilat: Inhibits both ACE and Neutral Endopeptidase.
18. Maprotiline: 2nd gen. antidepressant, with predominant NA reuptake inhibitor, little anticholinergic side effects, but may produce seizures.
19. Irinotecan: Topoisomerase 1 inhibitor, called CPT-11, a Camptothecin molecule, anti-leukemia agent, also useful in Colon carcinoma, producing a metabolite SN-38 which produces secretory diarrhoea manageable with Loperamide or Octreotide, and also myelosuppression especially with patients with deficient UGT1A1.
20. Dofetilide: Potassium Channel Blocker.
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