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Nagging Q Forum Hot - Library - Unanswered
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kumar123Send an Instant Message to kumar123  




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Quick Scroll Chargaff's rule 01.24.05 (3 years ago) #1

This was discussed before but I couldnt find that post anywhere
Chargaff's rule is-
A+G=T+C
A/T= G/C
A=T=G=C
A+T=G+C
Ans given is 2
Is it 1??
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Quick Scroll i think it is A=T,G=C 01.25.05 (3 years ago) #2

I REMEMBER reading in one of the question banks as in dna A=T G=C ---called as chargaff's rule ....correct me if wrong
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Quick Scroll 01.25.05 (3 years ago) #3

the answer should be 2 only yaar
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Quick Scroll 01.25.05 (3 years ago) #4

i agree
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Quick Scroll 01.25.05 (3 years ago) #5

one is also correct
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Quick Scroll 01.25.05 (3 years ago) #6

ans is A)
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Quick Scroll 01.25.05 (3 years ago) #7

Chargaff's Rule" Total Pyrimidines (C+T) = Total Purines (A+G) in DNA


A + G = C + T
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Quick Scroll 01.25.05 (3 years ago) #8

Chargaff's Rule states that total purines equals

total pyrimidines.

In dsDNA (or dsRNA) (ds = double stranded)

% A = % T (% U)

% G = % C

% purines = % pyrimidines

% A + % G = % T (% U) + % C


In other words 1 is definately the correct

answer !!!!
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Quick Scroll 01.26.05 (3 years ago) #9

Total purines(A+G)=Total pyrimidines(T+C)
which means that among 100 parts of DNA,50 will be accounted for by A+G and 50 by T+C So
A+G=T+C (STEP 1)
Taking this equation 1 step further,in 50 parts of DNA,25 will be accounted for by A and 25 by its complementary nucleotide T (The same holds for G and C)
So,
A(25 fractions) =T(25 fractions) =G(25 fractions) =C(25 fractions)

So,A=G=T=C

I'D GO FOR OPTION C
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Quick Scroll 01.26.05 (3 years ago) #10

MockTurtle when you took it to the next level you

also took it out of the limitations of the Chargaff's

rule .. no doubt you may be right but it doesn't

comply to Chargaff's rule anymore ... I still say

that the answer is definately 1 and hold my

stance !!!
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